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1

Planning for an adaptive design: a case study in COPD

B. Jones, G. Atkinson, J. Ward, E. Tan, T. Kerbusch

Journal:

Pharmaceutical Statistics

Year:

2006

Language:

english

File:

PDF, 202 KB

english, 2006

2

A searching procedure for transformations and models in a classical Mendelian cross breeding study

Sjeng Kerbusch, F. Josef Staay, Nelleke Hendriks

Journal:

Behavior Genetics

Year:

1981

Language:

english

File:

PDF, 863 KB

english, 1981

3

Determination of Ifosfamide, 2- and 3-Dechloroethyifosfamide Using Gas Chromatography With Nitrogen-Phosphorus or Mass Spectrometry Detection

Kerbusch, Thomas, Jeuken, Marie-Jos??, Derraz, Jamila, van Putten, John W. G., Huitema, Alwin D. R., Beijnen, Jos H.

Journal:

Therapeutic Drug Monitoring

Year:

2000

Language:

english

File:

PDF, 926 KB

english, 2000

4

Pharmacokinetic Interactions Between Mirabegron and Metformin, Warfarin, Digoxin or Combined Oral Contraceptives

Groen-Wijnberg, Monique, van Dijk, Jan, Krauwinkel, Walter, Kerbusch, Virginie, Meijer, John, Tretter, Reiner, Zhang, Wenhui, van Gelderen, Marcel

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

2017

Language:

english

File:

PDF, 1.47 MB

english, 2017

5

Notwendige Veränderungen für den Generationenwechsel

Schulze-Hulitz, Elisabeth, Kerbusch, Willy, Zimmermann, Sabine

Journal:

Innovative Verwaltung

Year:

2016

Language:

german

File:

PDF, 295 KB

german, 2016

6

Exposureâresponse characterisation of tildrakizumab in chronic plaque psoriasis: pooled analysis of three randomised controlled trials

Kerbusch, Thomas, Li, Hanbin, Wada, Russell, Jauslin, Petra M., Wenning, Larissa

Journal:

British Journal of Clinical Pharmacology

Year:

2020

Language:

english

File:

PDF, 1.53 MB

english, 2020

7

Artificial Intelligence and Machine Learning Applied at the Point of Care

Angehrn, Zuzanna, Haldna, Liina, Zandvliet, Anthe S., Gil Berglund, Eva, Zeeuw, Joost, Amzal, Billy, Cheung, S. Y. Amy, Polasek, Thomas M., Pfister, Marc, Kerbusch, Thomas, Heckman, Niedre M.

Journal:

Frontiers in Pharmacology

Year:

2020

File:

PDF, 381 KB

2020

8

Distribution of ifosfamide and metabolites between plasma and erythrocytes

T. Kerbusch, V.M.M. Herben, M-J.J. Jeuken, J. Ouwerkerk, H.J. Keizer, J.H. Beijnen

Journal:

Biopharmaceutics & Drug Disposition

Year:

2001

Language:

english

File:

PDF, 119 KB

english, 2001

9

The reaction between solid lead and chlorine gas

J.M.L. Kerbusch

Journal:

Journal of Solid State Chemistry

Year:

1974

Language:

english

File:

PDF, 365 KB

english, 1974

10

Effect of clarithromycin on the pharmacokinetics and pharmacodynamics of pimozide in healthy poor and extensive metabolizers of cytochrome P450 2D6 (CYP2D6)

DESTA, Z, KERBUSCH, T, FLOCKHART, D

Journal:

Clinical Pharmacology & Therapeutics

Year:

1999

Language:

english

File:

PDF, 152 KB

english, 1999

11

Sensitive assay for pimozide in human plasma using high-performance liquid chromatography with fluorescence detection: application to pharmacokinetic studies

Thomas Kerbusch, Zeruesenay Desta, Nadia V Soukhova, David Thacker, David A Flockhart

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1997

Language:

english

File:

PDF, 265 KB

english, 1997

12

Simultaneous determination of N,N′,N″-triethylenethiophosphoramide, cyclophosphamide and some of their metabolites in plasma using capillary gas chromatography

Alwin D.R. Huitema, Matthijs M. Tibben, Thomas Kerbusch, Jan W. Zwikker, Sjoerd Rodenhuis, Jos H. Beijnen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1998

Language:

english

File:

PDF, 141 KB

english, 1998

13

High-performance liquid chromatographic determination of stabilized 4-hydroxyifosfamide in human plasma and erythrocytes

Thomas Kerbusch, Alwin D.R Huitema, Jantien J Kettenes-van den Bosch, H.Jan Keizer, Jan Ouwerkerk, Jan de Kraker, Jos H Beijnen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1998

Language:

english

File:

PDF, 155 KB

english, 1998

14

Bayesian Pharmacokinetics of Lithium after an Acute Self-Intoxication and Subsequent Haemodialysis: A Case Report

Thomas Kerbusch, Ron A. A. Math, Hans M. M. B. Otten, Eelco W. Meesters, Hendrikus J. M. Van Kan, Jan H. M. Schellens, Jos H. Beijnen

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2002

Language:

english

File:

PDF, 49 KB

english, 2002

15

Evaluation of the autoinduction of ifosfamide metabolism by a population pharmacokinetic approach using NONMEM

T. Kerbusch, A. D. R. Huitema, J. Ouwerkerk, H. J. Keizer, R. A. A. Mathôt, J. H. M. Schellens, J. H. Beijnen

Journal:

British Journal of Clinical Pharmacology

Year:

2000

Language:

english

File:

PDF, 178 KB

english, 2000

16

Population pharmacokinetic modelling of darifenacin and its hydroxylated metabolite using pooled data, incorporating saturable first-pass metabolism, CYP2D6 genotype and formulation-dependent bioavailability

Thomas Kerbusch, Ulrika Wählby, Peter A. Milligan, Mats O. Karlsson

Journal:

British Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 5.92 MB

english, 2003

17

Assessment of the relative in vivo potency of the hydroxylated metabolite of darifenacin in its ability to decrease salivary flow using pooled population pharmacokinetic–pharmacodynamic data

Thomas Kerbusch, Peter A. Milligan, Mats O. Karlsson

Journal:

British Journal of Clinical Pharmacology

Year:

2004

Language:

english

File:

PDF, 2.02 MB

english, 2004

18

Assessing the efficiency of mixed effects modelling in quantifying metabolism based drug–drug interactions: using in vitro data as an aid to assess study power

Trevor N. Johnson, Thomas Kerbusch, Barry Jones, Geoffrey T. Tucker, Amin Rostami-Hodjegan, Peter A. Milligan

Journal:

Pharmaceutical Statistics

Year:

2009

Language:

english

File:

PDF, 299 KB

english, 2009

19

Genetics of absence epilepsy in rats

B. W. M. M. Peeters, J. M. L. Kerbusch, E. L. J. M. van Luijtelaar, J. M. H. Vossen, A. M. L. Coenen

Journal:

Behavior Genetics

Year:

1990

Language:

english

File:

PDF, 380 KB

english, 1990

20

Rapid acquisition of two-way active avoidance in inbred Roman Low Avoidance rats

F. Josef van der Staay, Wijnand Raaijmakers, Sjeng Kerbusch

Journal:

Behavior Genetics

Year:

1983

Language:

english

File:

PDF, 317 KB

english, 1983

21

The replicated diallel cross: A generalized method of analysis

W. E. Crusio, J. M. L. Kerbusch, J. H. F. van Abeelen

Journal:

Behavior Genetics

Year:

1984

Language:

english

File:

PDF, 1.30 MB

english, 1984

22

Genetics of spike-wave discharges in the electroencephalogram (EEG) of the WAG/Rij inbred rat strain: A classical mendelian crossbreeding study

B. W. M. M. Peeters, J. M. L. Kerbusch, A. M. L. Coenen, J. M. H. Vossen, E. L. J. M. van Luijtelaar

Journal:

Behavior Genetics

Year:

1992

Language:

english

File:

PDF, 429 KB

english, 1992

23

Genetic correlations in validating emotionality

J. Josef van der Staay, Sjeng Kerbusch, Wijnand Raaijmakers

Journal:

Behavior Genetics

Year:

1990

Language:

english

File:

PDF, 711 KB

english, 1990

24

Behavioral responses to novelty in mice: A reanalysis

J. M. L. Kerbusch, J. H. F. Abeelen

Journal:

Behavior Genetics

Year:

1981

Language:

english

File:

PDF, 227 KB

english, 1981

25

Translational PK–PD modelling of molecular target modulation for the AMPA receptor positive allosteric modulator Org 26576

Roberta Bursi, Gul Erdemli, Robert Campbell, Matthew M. Hutmacher, Thomas Kerbusch, David Spanswick, Ross Jeggo, Kari R. Nations, Peter Dogterom, Jacques Schipper, Mohammed Shahid

Journal:

Psychopharmacology

Year:

2011

Language:

english

File:

PDF, 556 KB

english, 2011

26

Reduction of cyclophosphamide bioactivation by thioTEPA: critical sequence-dependency in high-dose chemotherapy regimens

Alwin D. R. Huitema, Thomas Kerbusch, Matthijs M. Tibben, Sjoerd Rodenhuis, Jos H. Beijnen

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 146 KB

english, 2000

27

Population pharmacokinetics of ifosfamide and its 2- and 3-dechloroethylated and 4-hydroxylated metabolites in resistant small-cell lung cancer patients

Thomas Kerbusch, John W. van Putten, Harry J. Groen, Alwin D. Huitema, Ron A. Mathôt, Jos H. Beijnen

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 201 KB

english, 2001

28

Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies

Radojka M. Savic, Daniël M. Jonker, Thomas Kerbusch, Mats O. Karlsson

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2007

Language:

english

File:

PDF, 305 KB

english, 2007

29

Simple and selective determination of the cyclophosphamide metabolite phosphoramide mustard in human plasma using high-performance liquid chromatography

Alwin D.R Huitema, Matthijs M Tibben, Thomas Kerbusch, J Jantien Kettenes-van den Bosch, Sjoerd Rodenhuis, Jos H Beijnen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2000

Language:

english

File:

PDF, 651 KB

english, 2000

30

Population pharmacokinetic–pharmacodynamic analysis for sugammadex-mediated reversal of rocuronium-induced neuromuscular blockade

Huub J. Kleijn, Daniel P. Zollinger, Michiel W. van den Heuvel, Thomas Kerbusch

Journal:

British Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 2.50 MB

english, 2011

31

Modeling and Simulation of the Time Course of Asenapine Exposure Response and Dropout Patterns in Acute Schizophrenia

Friberg, LE, de Greef, R, Kerbusch, T, Karlsson, MO

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 551 KB

english, 2009

32

Phase I and pharmacokinetic study of the combination of topotecan and ifosfamide administered intravenously every 3 weeks

Kerbusch, T, Groenewegen, G, Mathôt, R A A, Herben, V M M, ten Bokkel Huinink, W W, Swart, M, Ambaum, B, Rosing, H, Jansen, S, Voest, E E, Beijnen, J H, Schellens, J H M

Journal:

British Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 173 KB

english, 2004

33

Modulation of the cytochrome P450–mediated metabolism of ifosfamide by ketoconazole and rifampin

Journal:

Clinical Pharmacology & Therapeutics

Year:

2001

Language:

english

File:

PDF, 143 KB

english, 2001

34

Genetic analysis of tolerance to ethanol hypothermia in recombinant inbred mice: Effect of desglycinamide(9)-Arginine(8)-vasopressin

John C. Crabbe, Henk Rigter, Sjeng Kerbusch

Journal:

Behavior Genetics

Year:

1980

Language:

english

File:

PDF, 760 KB

english, 1980

35

Population pharmacokinetics and exploratory pharmacodynamics of ifosfamide and metabolites after a 72-h continuous infusion in patients with soft tissue sarcoma

T., Kerbusch, R., Math&#x000F4, t, H., Keizer, J., Ouwerkerk, S., Rodenhuis, J., Schellens, J., Beijnen

Journal:

European Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 218 KB

english, 2001

36

Behavioral genetics: Volume 1, chapter 13, pp. 677–764 by Gerald E. McClearn and Terryl T. Foch

J.M.L. Kerbusch

Journal:

Acta Psychologica

Year:

1990

Language:

english

File:

PDF, 144 KB

english, 1990

37

Effects of chronic dietary choline on temporal discrimination of BN and WAG rats

F.Josef van der Staay, Wijnand G.M. Raaijmakers, Sjeng Kerbusch

Journal:

Physiology & Behavior

Year:

1992

Language:

english

File:

PDF, 1.02 MB

english, 1992

38

Problem-solving behaviour in apomorphine-susceptible and unsusceptible rats

Carla J.H. Coenders, Sjeng M.L. Kerbusch, Jo M.H. Vossen, Alexander R. Cools

Journal:

Physiology & Behavior

Year:

1992

Language:

english

File:

PDF, 549 KB

english, 1992

39

Chronic dietary choline enrichment affects DRL responding of old, but not of adult CPBB rats

F.Josef van der Staay, Wijnand Raaijmakers, Dorine Collijn, Sjeng Kerbusch

Journal:

Physiology & Behavior

Year:

1992

Language:

english

File:

PDF, 608 KB

english, 1992

40

Pharmacokinetic-pharmacodynamic modelling of the EGG effect of synthetic opioids: Correlation with receptor binding

E.H. Cox, T. Kerbusch, M. Danihol

Journal:

European Journal of Pharmaceutical Sciences

Year:

1996

Language:

english

File:

PDF, 138 KB

english, 1996

41

Effect of Renal or Hepatic Impairment on the Pharmacokinetics of Mirabegron

James Dickinson, Michaelene Lewand, Taiji Sawamoto, Walter Krauwinkel, Marloes Schaddelee, James Keirns, Virginie Kerbusch, Selina Moy, John Meijer, Donna Kowalski, Richard Morton, Kenneth Lasseter, D

Journal:

Clinical Drug Investigation

Year:

2013

Language:

english

File:

PDF, 395 KB

english, 2013

42

Analysis of behavioural responses to an ACTH analog in CXB/By recombinant inbred mice

John C. Crabbe, Henk Rigter, Sjeng Kerbusch

Journal:

Behavioural Brain Research

Year:

1982

Language:

english

File:

PDF, 1.33 MB

english, 1982

43

P.3.c.056 Population pharmacokinetics of asenapine in patients with schizophrenia or bipolar disorder

M. Prohn, R. De Greef, S. Chapel, T. Kerbusch

Journal:

European Neuropsychopharmacology

Year:

2009

Language:

english

File:

PDF, 200 KB

english, 2009

44

Synaptosomal uptake studies on recombinant inbred mice; neurotransmitter interaction and behavioral correlates

Hans Schoemaker, Victor J. Nickolson, Sjeng Kerbusch, John C. Crabbe

Journal:

Year:

1982

Language:

english

File:

PDF, 686 KB

english, 1982

45

Pharmacokinetic Properties of Mirabegron, a β3-Adrenoceptor Agonist: Results From Two Phase I, Randomized, Multiple-Dose Studies in Healthy Young and Elderly Men and Women

Krauwinkel, Walter, van Dijk, Jan, Schaddelee, Marloes, Eltink, Charlotte, Meijer, John, Strabach, Grégory, van Marle, Sjoerd, Kerbusch, Virginie, van Gelderen, Marcel

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.01 MB

english, 2012

46

Clinical Pharmacokinetics and Pharmacodynamics of Ifosfamide and its Metabolites

Dr Thomas Kerbusch, Jan de Kraker, H. Jan Keizer, John W. G. van Putten, Harry J. M. Groen, Rob L. H. Jansen, Jan H. M. Schellens, Jos H. Beijnen

Journal:

Clinical Pharmacokinetics

Year:

2001

Language:

english

File:

PDF, 288 KB

english, 2001

47

Population Pharmacokinetics of Ifosfamide and its Dechloroethylated and Hydroxylated Metabolites in Children with Malignant Disease

Dr Thomas Kerbusch, Jan de Kraker, Ron A. A. Mathôt, Jos H. Beijnen

Journal:

Clinical Pharmacokinetics

Year:

2001

Language:

english

File:

PDF, 208 KB

english, 2001

48

Bone Physiology, Disease and Treatment

Teun M. Post, Serge C. L. M. Cremers, Thomas Kerbusch, Professor Meindert Danhof

Journal:

Clinical Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 365 KB

english, 2010

49

Methods used for prevention of white spot lesion development during orthodontic treatment with fixed appliances

Kerbusch, Antoine E. G., Kuijpers-Jagtman, Anne M., Mulder, Jan, Sanden, Wil J. M. van der

Journal:

Acta Odontologica Scandinavica

Year:

2012

Language:

english

File:

PDF, 156 KB

english, 2012

50

Effects of Food Intake on the Pharmacokinetic Properties of Mirabegron Oral Controlled-Absorption System: A Single-Dose, Randomized, Crossover Study in Healthy Adults

Lee, Jennifer, Zhang, Wenhui, Moy, Selina, Kowalski, Donna, Kerbusch, Virginie, van Gelderen, Marcel, Sawamoto, Taiji, Grunenberg, Nicole, Keirns, James

Journal:

Clinical Therapeutics

Year:

2013

Language:

english

File:

PDF, 367 KB

english, 2013